Anandron® 50mg Blister

DIN

02221861

Size

Box of 90 (3 x 30 blister-packed) tablets

SKU

065914104756

Directions

Initial dosage: 300 mg once daily for the first month of treatment. Maintenance dosage: 150 mg once daily, may be started earlier should intolerance occur.

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INFORMATION FOR THE PATIENT

Anandron® (nilutamide) is indicated in the treatment of metastatic prostatic carcinoma (Stage D2) in conjunction with surgical castration.

This medication is typically used only once a day. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed.

It must be used regularly and continuously to maintain its beneficial effects. Be sure to keep an adequate supply on hand. This medication may be taken with or without food.

If you drink alcohol, moderate consumption is recommended. Talk to your pharmacist or doctor to find out exactly how much alcohol you can drink.

Side Effects

In addition to its desired action, this medication may cause some side effects, notably:

It may cause hot flashes;
It may cause constipation — to prevent this, drink plenty of water or juice, and eat more dietary fibre;
It may cause nausea or, rarely, vomiting;
It may cause vision problems;
It may affect your ability to see at night.

Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.

Storage

As with most medications, this product should be stored at room temperature. Store it in a secure location where it will not be exposed to excessive heat, moisture, or direct sunlight. Make sure that any leftover portion is disposed of safely.

ABOUT THE DISEASE

If your prostate cancer spreads to other parts of your body, your doctor may tell you that it’s “metastatic” or that your cancer has “metastasized.”

Most often, prostate cancer spreads to the bones or lymph nodes. It’s also common for it to spread to the liver or lungs. It’s rarer for it to move to other organs, such as the brain.

It’s still prostate cancer, even when it spreads. For example, metastatic prostate cancer in a bone in your hip is not bone cancer. It has the same prostate cancer cells the original tumor had.

Metastatic prostate cancer is an advanced form of cancer. There’s no cure, but you can treat it and control it. Most men with advanced prostate cancer live a normal life for many years.

The goals of treatment are to:

  • Manage symptoms
  • Slow the rate your cancer grows
  • Shrink the tumor

Some cancers are called “locally advanced.” That means the cancer has spread from the prostate to nearby tissue. It’s not the same as metastatic cancer since it hasn’t spread to other parts of your body. Many locally advanced prostate cancers can be cured.

How Prostate Cancer Spreads

Cancer cells sometimes break away from the original tumor and go to a blood or lymph vessel. Once there, they move through your body. The cells stop in capillaries — tiny blood vessels — at some distant location.

The cells then break through the wall of the blood vessel and attach to whatever tissue they find. They multiply and grow new blood vessels to bring nutrients to the new tumor. Prostate cancer prefers to grow in specific areas, such as lymph nodes or in the ribs, pelvic bones, and spine.

PATIENT RESOURCES

PRODUCT MONOGRAPH

Click here to download the Product Monograph

 

PRESCRIBING INFORMATION

Click here to download the prescribing information

 

FREQUENTLY ASKED QUESTIONS

What is Anandron® used for?

Anandron® is a medicine for treating prostate cancer in men. It contains the active ingredient nilutamide. Anandron® belongs to a family of medicines called non-steroidal anti-androgens. These medicines work by blocking the effect of androgen hormones that are naturally produced by your body. Prostate cancer cells are dependent on these hormones, and blocking their effect is intended to stop the growth of the cancer.

Anandron® is more effective when used at the same time as other medicines known generally as luteinizing hormone-releasing hormone (LHRH) agonists or, alternatively, following surgery designed to treat prostate cancer. Your doctor may have prescribed Anandron® for another reason. Ask your doctor if you have any questions about why Anandron® has been prescribed for you.

Anandron® is available only with a doctor’s prescription. Before using them, discuss any other drugs you may be taking or if you intend to use complementary medicines. It is difficult to predict how long Anandron will be effective for any given individual.

How is Anandron® given?
Treatment with Anandron® (nilutamide) should be initiated immediately after surgical castration. Initial dosage: 300 mg once daily for the first month of treatment. Maintenance dosage: 150 mg once daily, may be started earlier should intolerance occur. Anandron® should be taken before breakfast. Discontinuation of Anandron® should be considered once objective evidence of disease progression is noted.
What are the side effects of taking Anandron®?
Common adverse events include: hot flushes, impaired adaptation to darkness, nausea, alcohol intolerance, dizziness, chromatopsia, SGPT/SGOT increased, abnormal vision, photophobia, hyperglycemia, impotence, dyspnea, gynecomastia, impaired light adaptation, interstitial lung disease, eye disorder, libido decreased, sweating increased, vomiting, anorexia, blurred vision, hepatitis, hypertension, anemia, asthenia, gastrointestinal pain, lung disorder, malaise
Can I take Anandron® with my other medications?
Nilutamide may reduce the hepatic metabolism of warfarin-type anticoagulants, thereby delaying elimination and increasing blood levels of these drugs. The concomitant use of Anandron® with medicinal products known to prolong the QTc interval or medicinal products able to induce torsades de pointes should be carefully evaluated
What to do if you miss a dose?
If you miss a dose, take it as soon as you remember and then resume your normal dosing schedule. However, you should not take more than 300 mg of ANANDRON in any one day during the first four weeks of treatment or more than 150 mg in any one day thereafter.

Therefore, if it is almost time for your next dose when you remember that you have missed a dose, skip the dose you missed and take your next dose at the usual time (i.e. do not take a double dose). If you are concerned or if you have missed more than one dose, please speak to your doctor

What to do if you take too many tablets?
In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

If you take, by mistake, too many tablets on the same day, you may feel nauseous and dizzy, and you may vomit. These symptoms will normally go away after temporarily interrupting your treatment or reducing the dose, however these steps should only be taken on your doctor’s advice. If you have taken more than 300 mg in one day, you should contact your doctor as soon as possible.


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