Separator Gels in PRP Kits – The Advantages of a Physical Barrier

The market for Platelet-Rich Plasma (PRP) preparation systems has flourished in the last 10 years with companies offering diverse options to concentrate platelets and growth factors in innovative ways.

These options range from manual, open system kits with multiple steps that require a great deal of skill from the operator, to large automated, closed systems that require a lot of office space and a big budget. Of course, each system has its own advantages and disadvantages regarding price, versatility, or ease of use, but only a few options are flexible enough to be used in any sized practice in a quick and effective way.

Among these options, the separator gel system emerges as a potential option which covers the full spectrum from cost effectiveness to ease of use.

A Separator Gel creates a physical barrier that traps red blood cells and granulocytes below the gel, thereby maximizing the recovery of PRP in an effective manner while allowing plasma, platelets, monocytes and lymphocytes to float on top of it. Red blood cells and granulocytes do not induce regeneration and may contribute to a catabolic effect, thereby minimizing the efficacy of the PRP obtained.
Since the gel hardens automatically after centrifugation, the tube can be inverted to ensure an even platelet distribution within the resulting plasma. The gel also allows the operator to harvest the last drop of PRP. It is no surprise that gel tube systems yield higher platelet recovery rates as compared to non-gel systems.

The gel technology was introduced in Canada many years ago through blood collection systems, so most nurses are very familiar with the procedure. Over time, the gel composition and physical properties have been enhanced to create a new generation of gels that are specifically designed to maximize the quality of the final PRP product. The Advanced Separator Gel, a proprietary technology that is the core element of Revival PRP® Regenerative System technology, is the final expression in the evolution of gel systems.

Gel tube kits are pre-filled with citrate dextrose -A (ACD), which is the anticoagulant of choice due to its platelet-preserving properties. Pre-filled anticoagulant minimizes operator errors as operators do not have to introduce anticoagulant to the system.

Finally, the system contains the precise amount of vacuum required to draw an appropriate amount of the blood sample and maintain the correct sample to anticoagulant ratio. This eliminates the risk of excessive anticoagulation.

These are just some of the reasons why gel tube kits are becoming more popular with PRP practitioners world-wide, and products like Revival PRP® take PRP preparation to the next level of efficacy and quality.